Introduction

Homology modelling (or comparative modelling) is used to predict the structures of proteins by comparison to proteins of similar sequence and known structure.

For more information on the principles of homology modelling, please refer to the linked web page: Homology Modelling

 

More information on homology modelling can also be found in the following references:

1. Marti-Renom MA, Yerkovich B, Sali A. Comparative Protein Structure Prediction. Current Protocols in Protein Science. John Wiley & Sons, Inc.; 2001. 

2. Krieger E, Nabuurs SB, Vriend G. Homology Modeling. Structural Bioinformatics. John Wiley & Sons, Inc.; 2005. pp. 509–523. 

Computational Tools

Homology Modelling can be performed using the following software tools: